Japanese

Title	認知機能障害を有する患者の服薬管理に影響する因子の探索
Subtitle	原著
Authors	木ノ下智康1, 長谷川章2, 溝神文博2
Authors (kana)
Organization	1国立長寿医療研究センター 治験・臨床研究推進センター, 2国立長寿医療研究センター 薬剤部
Journal	日本老年薬学会雑誌
Volume	3
Number	3
Page	41-47
Year/Month	2020 /
Article	原著
Publisher	日本老年薬学会
Abstract	「緒言」 患者が医師の処方した薬を適切に服薬管理することは, 薬物治療を行う上で重要なことである. 服薬管理に影響をおよぼす因子として, 認知機能障害が報告されており, 認知症の中でも服薬管理能力の低下は早期に認められる症状であるが, 外来受診時に, 主治医が気づくことは, 稀である. 認知機能障害を有する患者の服薬管理に影響する因子の解明は, 服薬支援を行う上で有用な指標となることが期待される. 高齢者総合機能評価(Comprehensive geriatric assessment ; CGA)は, 多職種によって高齢者の身体機能, 精神・心理機能, 社会・経済状況を包括的に評価することにより, 種々の介入を行う老年医学的手法の1つである. CGA評価項目には, 認知機能を評価するMini mental state examination(MMSE), 基本的(Basic)activities of daily living(BADL)を評価するBarthel index, 手段的(Instrumental)ADLを評価するIADL, 意欲を評価するVitality index, 情緒・気分を評価するGeriatric depression scale(GDS)-15が含まれている.
Practice	薬学
Keywords	cognitive dysfunction, medication management, comprehensive geriatric assessment, long-term care insurance

English

Title	Exploration of Factors Affecting Medication Management in Patients with Cognitive Dysfunction
Subtitle	Original Paper
Authors	Tomoyasu Kinoshita1, Sho Hasegawa2, Fumihiro Mizokami2
Authors (kana)
Organization	1Innovation Center for Clinical Research, National Center for Geriatrics and Gerontology, 2Department of Pharmacy, National Center, for Geriatrics and Gerontology
Journal	Journal of Geriatric Pharmacy
Volume	3
Number	3
Page	41-47
Year/Month	2020 /
Article	Original article
Publisher	Japanese Society of Geriatric Pharmacy
Abstract	[Abstract] Aim: Elucidating factors affecting medication management in patients with cognitive dysfunction is useful toward providing support for those taking medication. In this study, we investigated factors affecting medication management in patients with cognitive dysfunction. Methods: From February 2013 to September 2017, a retrospective medical chart review was conducted. The survey items included age, sex, patient's educational level, number of daily doses, number of daily medications, frailty, vitality index, Barthel index, mini mental state examination (MMSE), instrumental activities of daily living (IADL) for each men and women, respective, geriatric depression scale (GDS)-15, long-term care insurance, use of medications three or more times a day, MMSE scores of 22 or less, women's IADL, and medication management. Results: Among 129 elderly patients (42 men and 87 women), use of medications three or more times a day, long-term care insurance, and women's IADL were involved in medication management. However, age, sex, patient's educational level, frailty, number of daily doses, number of daily medications, vitality index, Barthel index, and MMSE scores were not related to in medication management. The IADL scores were highest in women who did not use medications and had long-term care insurance. Conclusions: Factors affecting medication management in patients with cognitive dysfunction are the use of medications three or more times a day and independence in IALD in women who do not have long-term care insurance.
Practice	Pharmaceutical sciences
Keywords	cognitive dysfunction, medication management, comprehensive geriatric assessment, long-term care insurance

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