アブストラクト
| Title | COVID-19に伴う急性期・感染後神経系合併症とその病態 |
|---|---|
| Subtitle | 総説 |
| Authors | 和田義明 |
| Authors (kana) | |
| Organization | 日産厚生会 玉川病院 |
| Journal | 日本病院総合診療医学会雑誌 |
| Volume | 17 |
| Number | 2 |
| Page | 224-230 |
| Year/Month | 2021 / 3 |
| Article | 報告 |
| Publisher | 日本病院総合診療医学会 |
| Abstract | 「はじめに」Coronavirus disease 2019(COVID-19)は, 肺を主体とするウイルス感染症である. 肺炎を生じ重症化すれば人工呼吸器などを要する状態に至る. 一方, 味覚障害・嗅覚障害, 若年者での脳梗塞発症の報告などがあり, 神経症状が合併することが当初から知られている. 初期の中国のCOVID-19入院214例の検討では, めまい, 頭痛, 脳血管障害, 意識障害, けいれんなどの中枢神経症状は24.8%, 味覚障害, 嗅覚障害などを含む末梢神経障害は8.9%に認められており, 決して頻度が低い症状ではなく, 症状出現は重症者で増加することが報告されている. 急性期の中枢神経疾患としては, 脳血管障害, 髄膜脳炎, その他の脳症・脳炎として急性散在性脳脊髄炎, 急性出血性壊死性脳症などの報告がある. きわめてまれであるが, ミオクローヌスやパーキンソン症状の出現の報告もある. |
| Practice | 医学総合 |
| Keywords | COVID-19, 神経系合併症, 高次脳機能障害 |
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