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Alternatives to Animal Testing and Experimentation
Volume 4, Issue 3/4 / 1998
English Article Japanese Article
- Please note that metadata of J-type articlesare generated by machine-translation and the original texts are written in Japanese.
Availability of Serum from Clotted Rat Blood on Embryogenesis Miyuki KATOH, Reiko KIMURA, Ryuujirou SHOJI Alternatives to Animal Testing and Experimentation 4(3/4): 93-99, 1998. |
Toxicological and Pharmacological Evaluation of Xanthine Derivatives Using Chick Embryos As the Alternative Experimental Method Hiroyuki Miyazaki, Takashi Sugiyama, Hideyo Shimada Alternatives to Animal Testing and Experimentation 4(3/4): 101-109, 1998. |
Overview of the 10th annual meeting of Japanese Society of Alternatives to Animal Experiments Yasuo OHNO Alternatives to Animal Testing and Experimentation 4(3/4): 112-116, 1998. |
L-1. Criteria for the Validation and Regulatory Acceptance of Alternative Toxicological Testing Methods William S.STOKES Alternatives to Animal Testing and Experimentation 4(3/4): 117-118, 1998. |
SI-1. Studies on the Estimation of Hepatotoxicity of Agricultural Chemicals Using Hepatocytes Momoko SUNOUCHI, Yasuo OHNO Alternatives to Animal Testing and Experimentation 4(3/4): 118-119, 1998. |
SI-2. An Alternative Test for Neurotoxicity of Chemicals Using Cultured Pheochromocytoma PC12 Cells Kazuhide INOUE, Schuichi KOIZUMI, Tomoko OBAMA, Yasuo OHNO Alternatives to Animal Testing and Experimentation 4(3/4): 119-119, 1998. |
SI-3. Development of a New Evakuation Test of Genotoxicity Using Transgenic Mouse Technology Takehiko NOHMI1, Motoe KATOH2, Hiroshi SUZUKI3, Michiko MATSUI1, Masami YAMADA1, Masahiko WATANABE4, Makoto SUZUKI1, Naoko HORIYA5, Otsuya UEDA3, Toru SHIBUYA5, Hideo IKEDA6, Toshio SOFUNI1 Alternatives to Animal Testing and Experimentation 4(3/4): 119-120, 1998. |
SII-1. Evaluation and Prediction of Tissue Distribution of Drugs Using Cell Culture and Atably Transfected Expression Systems Hideyuki SAITO, Masahiro OKUDA, Ken-ichi INII Alternatives to Animal Testing and Experimentation 4(3/4): 120-121, 1998. |
SII-2. Genetic Regulation of Cisplatin-induced Apoptosis in Mouse Proximal Straight Tubule(S3) Cell Line Michio TAKEDA, Hitoshi ENDOU Alternatives to Animal Testing and Experimentation 4(3/4): 121-122, 1998. |
SII-3 In Vitro Drug Metabolism Study Using Recombinant Human P450 Expressed in Escherichia Coli Hirotaka KUSHIDA1, Tsutomu SAKUMA1, Tsuyoshi YOKOI1, Ken-ichi NUNOYA1, Yuko KONNO1, F.J.Gonzalez2, Toru ENDO3, Tetsuya KAMATSUKI1 Alternatives to Animal Testing and Experimentation 4(3/4): 123-123, 1998. |
SII-4. Establishment of Cell Lines Expressing Human CYP2E1 and Its Application for Toxicological Studies Tsuyoshi YOKOI1, Tetsuya NAKAGAWA1, Minoru SAWADA1, Ryoji ISHIDA2, Frank J.GONZALEZ3, Tetsuya KAMATAKI1 Alternatives to Animal Testing and Experimentation 4(3/4): 123-123, 1998. |
SII-5. High Level Expression if Human Drug Metabolizing Enzymes Integration into Drug Metabolism and Toxicity Charles L.CRESPI Alternatives to Animal Testing and Experimentation 4(3/4): 124-126, 1998. |
SIII-1. Alternatives in Medical Education Kazuyoshi MAEJIMA Alternatives to Animal Testing and Experimentation 4(3/4): 126-126, 1998. |
SIII-5. What Concerned Citizens Expect of Alternative Methods to Animal Experimentation Fusako Nogami Alternatives to Animal Testing and Experimentation 4(3/4): 127-128, 1998. |
Trends in Animal Alternatives and overview of 2nd World Congress on Alternatives and Animal Use in the Life Sciences Atsushige SATO1, Hiroshi ITAGAKI2 Alternatives to Animal Testing and Experimentation 4(3/4): 128-128, 1998. |
P-1. Modifying Effect of Anti-oxidation Agent on Photogenotoxicity Yuzuki NAKAGAWA, Shinobu WAKURI, Noriho TANAKA Alternatives to Animal Testing and Experimentation 4(3/4): 129-129, 1998. |
P2. Embryotrophic Activity of the Third Component of Complement in Post implantation Rat Embryo Culture Kazue SAKEMI, Makoto USAMI, Mitsuhiro TSUDA, Yasuo OHNO Alternatives to Animal Testing and Experimentation 4(3/4): 129-129, 1998. |
P3. Whole Embryonic Culture Method as an Alternative of Developmental Toxicity Test(1)-In the Case of Aminopyrene Atushi YOKOYAMA1, Masaharu AKITA1, Yukiaki KURODA2 Alternatives to Animal Testing and Experimentation 4(3/4): 130-130, 1998. |
P4. Effects of Salicylic Acid on the Nasal Placode in Cultured Rat Embryos Atushi YOKOYAMA1, Masaharu AKITA1, Yukiaki KURODA2 Alternatives to Animal Testing and Experimentation 4(3/4): 130-131, 1998. |
P5. Effects of Vitamin B or C on Cultured Rat Embryos Atushi YOKOYAMA1, Masaharu AKITA1, Yukiaki KURODA2 Alternatives to Animal Testing and Experimentation 4(3/4): 131-131, 1998. |
P6. Effects of Thalidomide on Cultured Rat Embryos in Newborn Calf Serum(2) Masaharu AKITA1, Atushi YOKOYAMA1, Yukiaki KURODA2 Alternatives to Animal Testing and Experimentation 4(3/4): 131-132, 1998. |
P7. Effects on Thalidomide on Cultured Rat Embryos- Cultured in Medium with Human Lympoblast Microsomes (Human UGT1*6) Masaharu AKITA1, Atushi YOKOYAMA1, Yukiaki KURODA2 Alternatives to Animal Testing and Experimentation 4(3/4): 132-133, 1998. |
P8. Whole embryo Culture for Assessment of the Developmental Toxicity Induced by the Drug Interactions Makiko KUWAGATA, Hiromasa TAKASHIMA, Tetsuji NAGAO Alternatives to Animal Testing and Experimentation 4(3/4): 133-134, 1998. |
P9. Evaluation of In Vitro Toxicity of MEIC Compounds on Human Natural Killer Cell Function Yoshiro KOBAYASHI1, Naoko WATANABE1, Tadao OHNO2 Alternatives to Animal Testing and Experimentation 4(3/4): 134-134, 1998. |
P10. Effect of Hapten Application on Langerhans Cells Migration from Skin Explant Yasunobu KOBAYASHI1, Mayumi KOTANI1 Alternatives to Animal Testing and Experimentation 4(3/4): 134-135, 1998. |
P11. Evaluation of In Vitro Methods as an Alternative to Phototoxicity Test Yuuko OKAMOTO, Akemi RYU, Tsuyoshi HEMMI, Sayako SHIMIZU, Kenji OHKOSHI Alternatives to Animal Testing and Experimentation 4(3/4): 135-135, 1998. |
P12. Alternative to Primary Draize Skin Irritation Test using Three-Dimensional Cultured Human Skin Model Katsuyasu MOROTA1, Shin-Ichiro MORITA1, Hajime KOJIMA2, Hiroaki KONISHI2, Takasige OKA1 Alternatives to Animal Testing and Experimentation 4(3/4): 135-136, 1998. |
P13. Evaluation of Alternative to Primary Draize Skin Irritation Test using Skin Model(EpiDerm) Michiru GENNO1, Ryohei YAMAMOTO1, Hajime KOJIMA2, Hiroaki KONISHI2, Mitch KLAUSNER3 Alternatives to Animal Testing and Experimentation 4(3/4): 136-137, 1998. |
P14. An Attempt at Cell Recovery Test Utilizing In Vitro Reconstructed Cell System Koichi IMAI, Masaaki NAKAMURA Alternatives to Animal Testing and Experimentation 4(3/4): 137-137, 1998. |
P15. Simultaneous evaluation of Cytotoxicity in the Neutral Red, MTT, and Crystal Violet Staining Assays in the Same Microplate Koji KAWAKAMI, Ikuyo MAKINO, Katsuyoshi CHIBA Alternatives to Animal Testing and Experimentation 4(3/4): 137-138, 1998. |
P17. A New Fluorometric Assay for Cell Proliferation and Viability Using Nucleic Acid Staining Agents Fuminori KATO, Mika TANAKA, Kyoko NAKAMURA Alternatives to Animal Testing and Experimentation 4(3/4): 138-138, 1998. |
P18. Histlogical Changes of Chorioallantoic Membrane (CAM) Caused by Surfactants Hiroshi Iimura1, Hisashi Tatsumi1, Hiroyoshi Ninomiya2 Alternatives to Animal Testing and Experimentation 4(3/4): 138-139, 1998. |
P19. An Assay for Developmental Toxicity with Cultured Cladoceran Eggs in vitro Toshihiro OHTA1, Shin-ichi TOKISHITA1, Yasuhiro SHIGA1, Takayuki HANAZATO2, Hideo YAMAGATA1 Alternatives to Animal Testing and Experimentation 4(3/4): 139-139, 1998. |
P20. Experimental Study Using Turkey as Alternative Animals Takashi SUGIYAMA, Kyoko GOTO, Satoshi USHIMARU, Hiroyuki MIYAZAKI, Hideyo SHIMADA Alternatives to Animal Testing and Experimentation 4(3/4): 139-140, 1998. |
P21. Pharmacological and Toxicological Studies Using Chick Embryos(10) Stud on Hypothyroid Models Takashi SUGIMURA1, Kazumi MORITA1, Kazuru SAITO2, Megumi SHIMADA2, Hideyo SHIMADA1,2 Alternatives to Animal Testing and Experimentation 4(3/4): 140-141, 1998. |
P22. Pharmacological and Toxicological Studies Using Chick Embryos(11) Effect of Temperature in Hemodynamic Changes of chick Embryos Kazuru SAITO2, Takashi SUGIMURA1, Megumi SHIMADA2, Hideyo SHIMADA1,2 Alternatives to Animal Testing and Experimentation 4(3/4): 141-142, 1998. |
P23. Detection of Environmental Pollutants Using Cultured Cells Shinobu WAKURI, Tamaki MAEDA, Makoto KAWAMURA, Atsuko TAKAHASHI, Noriho TANAKA Alternatives to Animal Testing and Experimentation 4(3/4): 142-143, 1998. |
P24. Evaluation of an Alternative to Skin Irritation Test (2):Determination of Pro-inflammatory Cytokine Gene Expression Michio SHIBATA, Takanari TSUDA, Hiroshi ITAGAKI, Hideyuki ICHIKAWA, Yoshihiro MORIKAWA Alternatives to Animal Testing and Experimentation 4(3/4): 143-144, 1998. |
P25. First Validation Study of Cyototoxicity Tests under JSAAE Project(Correction) Tadao OHNO1, 98 co-workers2 Alternatives to Animal Testing and Experimentation 4(3/4): 144-145, 1998. |
P26. Inter-laboratory Validation of Alternative Methods to Eye Irritation Test for Safety Evaluation of Cosmetic Ingredients (1) Evaluation of Chorioallantoic Membrane (CAM) Test Shigenobu HAGINO1,2, Shigemi KINOSHITA1,3, Naoko TANI1,3, Tsuneaki NAKAMURA1,4, Naoko ONO1,4, Kimiyo KONISHI, Hiroshi IIMURA1,5, Hajime KOJIMA1,6, Yasuo OHNO7 Alternatives to Animal Testing and Experimentation 4(3/4): 145-146, 1998. |
P27. Eye Irritation Test for Safety Evaluation of Cosmetic Ingredients (2) Evaluation of Red Blood Cell Hemolysis Test Yuuko OKAMOTO1,2, Kenji OHKOSHI1,2, Yutaka KASAI1,3, Junko OHUCHI1,3, Hiroshi KAKISHIMA1,4, Tomoyasu OGAWA1,4, Tohru TANAKA1,5, Hajime KOJIMA1,6, Toyozo KANEKO7, Yuko MATSUSHIMA7, Yasuo OHNO8 Alternatives to Animal Testing and Experimentation 4(3/4): 146-146, 1998. |
P28. Inter-laboratories Validation of Alternative Methods to Eye Irritation Test for Safety Evaluation of Cosmetic Ingredients (3) Evaluation of Hemoglobin Denaturation Test Masato HATAO1,2, Kazutami SAKAMOTO1,3, Miyuki OHNUMA1,3, Yoshiaki KAWASAKI1,3, Hiroshi KAKISHIMA1,4, Tomoyasu OGAWA1,4, Hajime KOJIMA1,5, Katsuyoshi CHIBA1,6, Kazuhiko YOSHIZAWA1,6, Toyozo KANEKO7, Junko MOMMA7, Yasuo OHNO8 Alternatives to Animal Testing and Experimentation 4(3/4): 146-147, 1998. |
P29. Inter-laboratory Validation of Alternative Methods to Eye Irritation Test for Safety Evaluation of Cosmetic Ingredients (4) Evaluation of Skin2(TM)ZK1100 and ZK1200 Models Akihiro KURISHITA1,2, Michiko SHIBATA1,3, Yuji KUWAHARA1,4, Hiroshi KAKISHIMA1,4, Yumiko MORITO1,5, Yuko OKAMOTO1,5, Kenji OHKOSHI1,5, Tsuneaki NAKAMURA1,6, Akiko MIZUTANI1,6, Masahito USAMI1,7, Miki SAITO1,8, Yoriko KADOTA1,8, Norikazu IKEDA1,8, Naoki HAYASHI9, Minoru KATAGIRI9, Akihiko HIROSE10, Toyozo KANEKO10, Yasuo OHNO11 Alternatives to Animal Testing and Experimentation 4(3/4): 147-148, 1998. |
P30. Eye Irritation Test for Safety Evaluation of Cosmetic Ingredients (5) Evaluation of Matrex(TM) Junko OHUCHI1,2, Yutaka KASAI1,2, Kazutami SAKAMOTO1,3, Miyuki OHNUMA1,3, Misato KITAMURA1,3, Hiroshi KAKISHIMA, Keiko SUZUKI1,4, Hirohumi KUWAHARA1,4, Yutaka IMANISHI1,5, Hisashi TATSUMI1,6, Mayumi KOTANI1,6, Kaori INOUE1,7, Hidenobu OKUMURA1,8, Masaki ARASHIMA1,8, Shigemi KINOSHITA1,9, Naoko TANI1,9, Hajime KOJIMA1,10, Tuneaki NAKAMURA1,11, Kouichi SUZUKI1,11, Takuya ISHIBASHI12, Hidekazu TAKAHASHI12, Yuki KITANO12, Yasuo OHNO13 Alternatives to Animal Testing and Experimentation 4(3/4): 148-149, 1998. |
P31. Eye Irritation Test for Safety Evaluation of Cosmetic Ingredients (6) Evaluation of Cytotoxicity Test on CornePack(R) Takashi UCHIYAMA1,2, Junichi AKIYAMA1,2, Eriko MIYAI1,2, Norikazu IKEDA1,3, Yoriko SUMIDA1,3, Katsuyoshi CHIBA1,4, Koji KAWAKAMI1,4, Ryohei YAMAMOTO5, Hisashi TORISHIMA5, Hiroshi YANASE5, Atsuko MIYAJIMA6, Momoko SUNOUCHI6, Yasuo OHNO6 Alternatives to Animal Testing and Experimentation 4(3/4): 149-150, 1998. |
P32. Inter-laboratory Validation of Alternative Methods to Eye Irritation Test for Safety Evaluation of Cosmetic Ingredients (7) Evaluation of Cytotoxicity Tests on SIRC Cells Naoko TANI1,2, Shigemi KINOSHITA1,2, Yuko OKAMOTO1,3, Mayumi KOTANI1,4, Hiroshi ITAGAKI1,5, Masahito USAMI1,6, Kumiko KATO1,6, Tadao OHNO7, Kaoru SAIJO7, Mayako KATO7, Yasuo OHNO8 Alternatives to Animal Testing and Experimentation 4(3/4): 150-150, 1998. |
P33. Inter-laboratory Validation of Alternative Methods to Eye Irritation Test for Safety Evaluation of Cosmetic Ingredients (8) Evaluation of Cytotoxicity Test on HeLa Cells Katsuyoshi CHIBA1,2, Ikuyo MAKINO1,2, Junko OHUCHl1,3, Yutaka KASAI1,3, Takashi UCHIYAMA1,4, Eriko MIYAI1,4, Hajime KOJIMA1,5, Masahito USAMI1,6, Kumiko KATOH1,6, Hiroyuki OHOSAWA1,7, Yasuo OHNO8 Alternatives to Animal Testing and Experimentation 4(3/4): 150-151, 1998. |
P34. Inter-laborato Validation of Alternative Methods to Eye Irritation Test for Safety Evaluation of Cosmetic Ingredients (9) Evaluation of Cytotoxicity Test on CHL Cells Hidenobu OKUMURA1,2, Mayumi KOTANI1,3, Hajime KOJIMA1,4, Momoko SUNOUCH5, Atsuko MIYAJIMA5, Yasuo OHNO5 Alternatives to Animal Testing and Experimentation 4(3/4): 151-152, 1998. |
P35. Inter-laboratory Validation of Alternative Methods to Eye Irritation Test for Safety Evaluation of Cosmetic Ingredients (10) Evaluation of EYTEX Kiyoji MATSUKAWA1,2, Kunio MASUDA1,2, Hiroshi KAKISHIMA1,3, Keiko SUZUKI1,3, Tomoaki OGAWA1,3, Yasuyo NAKAGAWA1,3, Chiho MATSUSHIGE1,4, Yutaka IMANISHI1,4, Tsuneaki NAKAMURA1,5, Akiko MIZUTANI1,5, Rie WATANABE1,6, Teruo SHINGAI7, Toyozo KANEKO8, Akihiko HIROSE8, Yasuo OHNO9 Alternatives to Animal Testing and Experimentation 4(3/4): 152-152, 1998. |
P36. Inter-laborator Validation of Alternative Methods to Eye Irritation Test for Safety Evaluation of Cosmetic Ingredients (11) Results of Draize Eye Irritation Test and Implication of Their Validation Toyozo KANEKO1, Junko MOMMA1, Junko KUMAKAWA1, Tohru INOUE1, Toshio SUZUKI2, Hiroshi KAKISHIMA3,4, Tsuneaki NAKAMURA3,5, Hisashi TATSUMI3,6, Shigenobu HAGINO3,7, Yasuo OHNO8 Alternatives to Animal Testing and Experimentation 4(3/4): 153-153, 1998. |
P37. Development of Drug Metabolism Simulator Using Three-Dimensional Culture of Hepatocyte-Studying of Induction on Drug Metabolic Enzymes Using PUF/spheroid Cultured Hepatocyte Hiroshi MIZUMOTO, Kohji NAKAZAWA, Taku MATSUSHIT, Kazumori FUNATSU Alternatives to Animal Testing and Experimentation 4(3/4): 153-154, 1998. |
P38. Development of Drug Metabolism Simulator for Alternatives to Animal Experimentation Using 3-Dimensional Culture of Hepatocytes Kohji MAKAZAWA, Hiroshi Mizumoto, Taku MATSUSHITA, Kazumori FUNATSU Alternatives to Animal Testing and Experimentation 4(3/4): 154-154, 1998. |
P39. A Simple Method for Screening Assessment of Acute Toxicity of Chemicals Sumie YAMANAKA1, Kaoru OHOTA1, Yoshinori TAKAESU1, Yuji KUROKAWA2, Tohru INOUE2, Katsushi NAITO2, Osayuki UCHIDA2, Hiroshi ONO3, Hideo KATSUMURA3, Jun KAGAWA4, Shigeru MORINOBU4, Masaki KATADA4 Alternatives to Animal Testing and Experimentation 4(3/4): 154-155, 1998. |
P40. Application of Dermal Papilla Cells for the Living Skin Equivalent Hidekazu TAKAHASHI, Yuki KITANO, Takuya ISHIBASHI, Yoshihisa KAWAMURA Alternatives to Animal Testing and Experimentation 4(3/4): 155-155, 1998. |